Just installed Oracle VirtualBox on SUSE Linux Enterprise Desktop 11. Got the following error upon running:

ish@inote:~> virtualbox
/usr/bin/virtualbox: line 77: /usr/lib/virtualbox/VirtualBox: Permission denied
/usr/bin/virtualbox: line 77: exec: /usr/lib/virtualbox/VirtualBox: cannot execute%

Gave execute rights to /usr/lib/virtualbox/VirtualBox and it starts correctly.

chmod +x /usr/lib/virtualbox/VirtualBox